Found 63 matching trials
Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse
PHASE1To test the preliminary efficacy of 16.0 mg of Prazosin daily versus placeb...
Location
Yale University School of Medicine: Yale Stress Center
Varenicline + Prazosin for Heavy Drinking Smokers
EARLY_PHASE1The purpose of this study is to examine the effect of varenicline and prazo...
Location
Yale University School of Medicine
Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse
PHASE2Cocaine use disorders affect approximately 1.5 million Americans annually. ...
Location
Michael E. DeBakey VA Medical Center, Houston, TX
Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment
PHASE1Double-blind, placebo-controlled, cross-over design study examining the eff...
Location
University of Wisconsin
Prazosin for Alcohol Use Disorder With Withdrawal Symptoms
PHASE2This is a Phase 2 single site randomized clinical trial (RCT) to be support...
Location
The Yale Stress Center: Yale University
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
PHASE3Prazosin is an alpha-1 adrenergic receptor antagonist that has been used su...
Location
VA Connecticut Healthcare System
Testing Doxazosin to Treat Stress Mechanisms in Alcoholism
PHASE2Double-blind, placebo controlled, randomized controlled trial (RCT) for Alc...
Location
University of Wisconsin
Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests
PHASE3Post-traumatic stress disorder (PTSD) affects many individuals who experien...
Status
Active Not Recruiting
Location
VA Puget Sound Health Care System Seattle Division, Seattle, WA
Optimum Treatment for Drug-Resistant Hypertension
PHASE4This study was recommended by NICE, as part of its 2006 guidance for the tr...
Effects of Prazosin on the Attention-Enhancing Effects of Nicotine
NATo test whether specific aspects of the attention-enhancing effects of nico...
Location
Multiple Locations